Interactive Session - Preimplantation Genetic Diagnosis - The Near Future

Date:October 21, 2014

Time:1:15 pm - 2:15 pm

Location:HCC320 - Hawaii Convention Center

Presenters

Santiago Munné, Ph.D. (Chair), Reprogenetics

Dagan Wells, Ph.D., Reprogenetics

Russell Durrett, Recombine

Moses Cesario, M.S., Previvo Genetics


(Alternate Panel)

Needs Assessment and Description
Different waves of technology have shaped the genetic analysis of embryos, from micromanipulation to sequencing. This session for laboratory scientists and reproductive health-care clinicians will debate the options feasible with current technology trends. Will genetics be needed once we know the function of the DNA code, and is this disruptive? Will all IVF cycles employ preimplantation genetic diagnosis (PGD), or will IVF even be needed? 

Learning Objectives
At the conclusion of this session, participants should be able to: 

  1. Discuss the future of in vitro fertilization and the role of PGD. 
  2. Explore the interdisciplinary advances in genetic analysis. 

ACGME Competency
Practice-based Learning and Improvement 

TEST QUESTION
Once complete sequencing of embryos is available, would it have a use?
a. It is cheaper to test the parents (2 samples) and do preimplantation genetic diagnosis (PGD) for a specific gene defect than a whole sequence of all embryos (6 samples average).
b. Whole sequencing of embryos is preferred as it detects de novo abnormalities.
c. There are no distinct differences in efficiency for sequencing the whole genome of embryos vs. PGD.

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