Plenary Lecture 6 - Systems Biology of Endometriosis

Date:October 21, 2014

Time:2:45 pm - 3:30 pm

Location:HCC Ballroom - Hawaii Convention Center

Presenters

Linda G. Griffith, Ph.D., Massachusetts Institute of Technology

Supporters

Endowed by a 1982 grant from EMD Serono, Inc.

Needs Assessment and Description
Genomic, proteomic, and other highly multiplexed molecular measurements are increasingly being applied to gain biological insight into endometriosis. These methods also have potential implications in clinical management of disease, including classifying patients for therapy. This session will provide clinicians and researchers with context for how to bridge between basic science and clinical use as these methods continue to advance. 

Learning Objectives
At the conclusion of this session, participants should be able to: 

  1. Explain how computational systems biology approaches are being used to classify disease processes in endometriosis patients. 
  2. Explain how computational systems biology approaches can potentially identify disease mechanisms in endometriosis. 
ACGME Competency
Medical Knowledge 

TEST QUESTION
Genome-wide association studies of patients with endometriosis have resulted in a genetic test, which, when combined with a blood test for a set of biomarkers:
a. Can diagnose endometriosis preoperatively, but only for deep infiltrating endometriosis
b. Can diagnose endometriosis preoperatively, but only for patients with endometriomas
c. Cannot diagnose endometriosis preoperatively

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