Afternoon Symposium - ALMER Symposium: PCOS from a Worldwide Perspective

Date:October 21, 2014

Time:4:15 pm - 6:15 pm

Location:HCC302 - Hawaii Convention Center

Presenters

J. Ricardo Loret de Mola, M.D., Southern Illinois University

Marcelo Barrionuevo, M.D., IVF FLORIDA Reproductive Associates

Richard Legro, M.D., Pennsylvania State University

Carlos Moran, M.D., Mexican Institute of Social Security

Teresa Sir-Petermann, M.D., University of Chile

Needs Assessment and Description
Polycystic ovary syndrome (PCOS) is an enigmatic disease associated with significant morbidity and reduction of fertility among women of reproductive age. Evidence suggests that the maternal-fetal environment plays an important role in the developmental programming of adult PCOS. Fetal androgen excess from congenital adrenal hyperplasia or virilizing tumors precede the development of PCOS-like symptoms after birth, while fetal metabolic, hormonal, and ovarian dysfunction also accompany gestational diabetes, which is common in PCOS mothers. There are clear clinical differences in how the disease affects different populations. These differences relate to the metabolic impact of PCOS and are particularly important in Latin-American countries. Although it has long been suggested that genetics play a role in the condition, recent data suggest a more important involvement in the genesis of the disease. 

This educational activity is intended for obstetricians, gynecologists, reproductive endocrinologists, infertility specialists, and other health-care professionals involved in the diagnosis and treatment of PCOS, with emphasis on the fundamental skills essential for diagnosis, evaluation, and adequate treatment(s). By applying key concepts and employing fundamental techniques, health-care professionals will be able to effectively diagnose, wisely treat, and optimize outcomes in their affected patients. 

Learning Objectives
At the conclusion of this session, participants should be able to: 

  1. Summarize recent PCOS genetic data from a worldwide population. 
  2. Describe how the environment affects the expression of PCOS and its effects during pregnancy, childhood, and adulthood. 
  3. Discuss the impact of ethnic differences among patients with PCOS. 

ACGME Competency
Practice-based Learning and Improvement 

TEST QUESTION
An 18-year-old woman with a history of hirsutism since puberty continues to worsen in her condition despite therapy with combined oral contraceptives. On physical exam she has sideburns and dark facial hair on her upper lip, chest, and abdomen. She has no evidence of acanthosis nigricans or clitoromegaly. After participating in this session, in my practice I will order the following test to make her diagnosis:
a. Follicle-stimulating hormone (FSH)
b. Dehydroepiandrosterone sulfate
c. Random serum cortisol
d. 17a-hydroxyprogesterone
e. Not applicable to my area of practice

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