Embryo Freezing/Thawing
Our question refers to the CPT code 89258 “Cryopreservation; Embryo(s)” and 89352 “Thawing of Cryopreserved; Embryo”. Our question is when we cryopreserve embryos for a patient on multiple devices (CryoLock, CryoTip, CryoLef, etc. whichever device the laboratory is using), is it appropriate to charge the patient per device using this code? We are using more than one device and also using media with the suggested protocol per device, so we would ideally like to charge for the cryopreservation of embryos per device. This question then also leads into thawing. If a patient requests to have two devices thawed for an FET (frozen embryo transfer) how can we charge per device when thawing embryos?
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Coding Q&A
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Appropriate Use of Modifier -25
Is Modifier -25 appropriate in the monitoring cycle when an ultrasound
How to bill for an FET
Is there a new update to the 89272 code that allows its use without
Codes for Embryo Biopsy
When doing a preimplantation genetic test (PGT) biopsy, can you bill for each day a biopsy is performed or can you only bill once for the cycle?
Billing for assisted hatching at biopsy and transfer
We would also like to know if you can bill assisted hatching with biopsy and then assisted hatching again during the transfer cycle.Coding Corner
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Topic Resources
View more on the topic of cryopreservation
Oocyte cryopreservation
We code 89337 (cryopreservation of oocytes) for the entire oocyte preservation cycle, including monitoring visits. View the Answer
TESE test thaws
We perform test thaws to determine if frozen TESE specimens from other clinics are suitable for our procedures. View the Answer
Billing for cryopreservation procedures on different days
I understand that if cryopreservation of oocytes is performed on two separate dates of service, each date of service was billable. View the Answer
Coding for ovarian tissue cryopreservation
For Cryopreservation; Reproductive Tissue Ovarian- 0058T code is not being recognized. Is there an updated one being used or a replacement of this code? View the Answer
Reimbursement for cost of donor egg
My wife and I are going through a fertility treatment process, and we have purchased a donor egg out-of-pocket from a donor bank. View the Answer
Coding for Ovarian tissue cryopreservation, experimental or not?
For Cryopreservation; Reproductive Tissue Ovarian- 0058T code is not being recognized. Is there an updated one being used or a replacement of this code? View the Answer
Does the number of eggs being frozen matter?
There is currently only one CPT code for the cryopreservation of mature oocytes and embryos. View the Answer
Semen Freezing
We have a couple who are doing an IUI cycle. View the Answer
Sperm Prep in Office vs. Lab
What are the codes for sperm washing when performed in the office vs in a CLIA certified lab? View the Answer
Sperm Preparation IUI and IVF
What semen analysis codes apply to sperm preparation for IUI or IVF? View the Answer
Reproductive Tissue Storage
What are the CPT codes for the Storage of Reproductive Cells/Tissues? View the Answer
In Vitro Maturation
Have CPT codes been established for maturation in vitro? View the Answer
IVF Case Rates
What ICD-10 codes apply to case rates? View the Answer
Office Testicular Aspiration
We are inquiring about a coding question for testicular aspirations. View the Answer
Oocyte Preservation Consult
Our center performs oocyte preservation procedures for women looking to preserve their fertility. View the Answer
Embryo Freezing/Thawing
Our question refers to the CPT code 89258 “Cryopreservation; Embryo(s)” and 89352 “Thawing of Cryopreserved; Embryo”. View the Answer
Embryo Storage Fees For Multiple Cycles
We bill embryo storage 89342 for a year's storage. View the Answer
Frozen Embryo Transport
What is the code for the cost of frozen embryo transport? View the Answer
Gamete Thawing/Warming
Can patients be charged for each vial/straw of reproductive gametes or tissues thawed? View the Answer
Coding For Ovarian Tissue Cryopreservation
Now that ASRM has removed the "experimental" designation from ovarian tissue cryopreservation what CPT code should be used instead of 0058T? View the Answer
Cryopreservation/Vitrification Oocytes/Embryos
What are the correct codes for cryopreservation/Vitrification Oocytes/Embryos? View the Answer
Cryopreservation/Vitrification Sperm/Testicular Tissues
What are the correct codes for the Cryopreservation/Vitrification of Sperm or testicular tissues? View the Answer
Billing For Cryopreservation Of Embryos Under The Male Partner
Can 89258 be billed under the male partner of a female patient? View the Answer
Coding For Long-Term Storage Of Embryos
We have recently been contacted by a payer stating we have a patient whose plan will cover long-term storage of her embryos. View the Answer
Journal Club Global: Should everyone freeze oocytes by age 33?
Oocyte cryopreservation is one of the fastest growing areas of reproductive medicine. View the Video
Ethical issues in oocyte banking for nonautologous use: an Ethics Committee opinion (2021)
Medical guidelines applicable to women donating fresh oocytes should also apply to women donating oocytes to an oocyte bank. View the Committee Opinion
Evidence-based outcomes after oocyte cryopreservation for donor oocyte in vitro fertilization and planned oocyte cryopreservation: a guideline (2021)
A review of success rates, factors that may impact success rates, and outcomes. View the Committee Opinion
Development of an emergency plan for in vitro fertilization programs: a committee opinion (2021)
All IVF programs and clinics should have a plan to protect fresh and cryopreserved human specimens (embryos, oocytes, sperm). View the Committee Opinion
Cryostorage of reproductive tissues in the in vitro fertilization laboratory: a committee opinion (2020)
This document is designed to assist IVF clinics in the management of cryopreserved reproductive tissues stored in cryogenic storage. View the Committee Opinion
Fertility preservation and reproduction in patients facing gonadotoxic therapies: an Ethics Committee opinion (2018)
Chemotherapy and radiation therapy often result in reduced fertility. View the Committee Opinion
Best practices of ASRM and ESHRE: a journey through reproductive medicine (2012)
ASRM and ESHRE are the two largest societies in the world whose members comprise the major experts and professionals working in reproductive medicine. View the Committee Joint GuidelineTopic Resources
View more on the topic of embryo
How to bill for an FET
Is there a new update to the 89272 code that allows its use without View the Answer
Codes for Embryo Biopsy
When doing a preimplantation genetic test (PGT) biopsy, can you bill for each day a biopsy is performed or can you only bill once for the cycle? View the Answer
Billing for assisted hatching at biopsy and transfer
We would also like to know if you can bill assisted hatching with biopsy and then assisted hatching again during the transfer cycle. View the Answer
ASRM Files Amicus Brief in Texas Embryo Case
ASRM has filed an amicus curiae (friend of the court) brief in the case of Antoun v Antoun, which is pending before the Texas Supreme Court.
View the Press Release
Alabama Supreme Court Rules Frozen Embryos are “Unborn Children” and admonishes IVF’s “Wild West” treatment
Legally Speaking™ on presenting facts and reflecting on the impact and potential implications of legal developments in ART. View the Column
Shipping of frozen embryos
I have some infertility coverage, under which my insurance said they will cover frozen embryo shipping/transport from one facility to another. View the Answer
Clinical management of mosaic results from preimplantation genetic testing for aneuploidy of blastocysts: a committee opinion (2023)
This document incorporates studies about mosaic embryo transfer and provides evidence-based considerations for embryos with mosaic results on PGT-A. View the Committee Opinion
Frozen Embryo Destruction and Potential Travel Restrictions for Surrogacy Arrangements
Legally Speaking™ focuses on the impact and the potential implications of legal developments on the assisted reproductive technologies. View the Column
Journal Club Global: Transferencia de embriones frescos versus congelados: ¿Cuál es la mejor opción
Los resultados de nuevas técnicas de investigación clínica que utilizan información de bancos nacionales de vigilancia médica. View the Video
Defining embryo donation: an Ethics Committee opinion (2023)
The ethical appropriateness of patients donating embryos to other patients for family building, or for research, is well established.
View the Committee Opinion
Does the number of eggs being frozen matter?
There is currently only one CPT code for the cryopreservation of mature oocytes and embryos. View the Answer
Reproductive Tissue Storage
What are the CPT codes for the Storage of Reproductive Cells/Tissues? View the Answer
Lab RVUs
Is there a list of RVUs for embryology and andrology laboratory procedures, and if so, where can it be found? View the Answer
ICSI and Embryo Biopsy
How to bill for ICSI or embryo biopsies that occur in different days? View the Answer
Embryo Biopsy
Have any new codes been introduced for the lab portion of PGT? View the Answer
Embryo Biopsy Embryologist Travel Costs
Can we bill insurance for the biopsy procedure? Can we bill for travel expenses? View the Answer
Embryo Biopsy PGS Testing
What codes are appropriate for PGS testing? View the Answer
Embryo Co-culture
Can codes 89250 and 89251 be billed on different days of the same cycle? View the Answer
Embryo Culture Denied As Experimental
We have received denials from insurance payers when billing CPT code 89251. View the Answer
Embryo Culture Less Than And More Than Four Days
When coding 89250 culture of oocytes/embryo <4 days, should that code be submitted to the insurance company for each of the days? View the Answer
Embryo Storage Fees For Multiple Cycles
We bill embryo storage 89342 for a year's storage. View the Answer
Embryo Thawing/Warming
Is it allowable to bill 89250 for the culture of embryos after thaw for a frozen embryo transfer (FET) cycle? View the Answer
Gamete Thawing/Warming
Can patients be charged for each vial/straw of reproductive gametes or tissues thawed? View the Answer
D&C Under Ultrasound Guidance
What are the CPT codes and ICD-10 codes for coding a surgical case for a patient with history of Stage B adenocarcinoma of the cervix ... View the Answer
Assisted Hatching Billed With Embryo Biopsy
Do you know if both assisted hatching (89253) and embryo biopsy for PGS/PGD/CCS (89290/89291) can be billed during the same cycle? View the Answer
Assisted Zona Hatching
Can assisted hatching and embryo biopsy for PGT-A; PGT-M or PGT-SR be billed during the same cycle? View the Answer
Billing For Cryopreservation Of Embryos Under The Male Partner
Can 89258 be billed under the male partner of a female patient? View the Answer
Embryo Transfer
A summary of Embryo Transfer codes collected by the ASRM Coding Committee View the Coding Summary
Colorado court balances religious and secular beliefs in frozen embryo divorce dispute
The day before the Dobbs decision, the Colorado Court of Appeals ruled on a divorcing couple’s disputed control over their frozen embryos. View the Legally Speaking
Journal Club Global: Is PGT-P cutting edge or should we cut it out?
PGT for polygenic risk scoring (PGT-P) is a novel screening strategy of embryos for polygenic conditions and traits. View the Video
Disposition of unclaimed embryos: an Ethics Committee opinion
Programs should create and enforce written policies addressing the designation, retention, and disposal of unclaimed embryos. View the Committee Opinion
A review of best practices of rapid-cooling vitrification for oocytes and embryos: a committee opinion (2021)
The focus of this paper is to review best practices for rapid-cooling cryopreservation of oocytes and embryos. View the Committee Opinion
Ethics in embryo research: a position statement by the ASRM Ethics in Embryo Research Task Force and the ASRM Ethics Committee (2020)
Scientific research using human embryos advances human health and offspring well-being and provides vital insights into the mechanisms for reproduction and disease. Research involving human embryos is ethically acceptable if it is likely to provide significant new knowledge that may benefit human health, well-being of the offspring, or reproduction. View the Committee Opinion
Guidance for Providers Caring for Women and Men Of Reproductive Age with Possible Zika Virus Exposure (Updated 2019)
This ASRM guidance specifically addresses Zika virus infection issues and concerns of individuals undergoing assisted reproductive technologies (ART). View the Guideline
Blastocyst culture and transfer in clinically assisted reproduction: a committee opinion (2018)
The purposes of this document is to review the literature regarding the clinical application of blastocyst transfer. View the Committee Opinion
Posthumous retrieval and use of gametes or embryos: an Ethics Committee opinion (2018)
Posthumous gamete (sperm or oocyte) retrieval or use for reproductive purposes is ethically justifiable if written documentation from the deceased authorizing the procedure is available. View the Committee Opinion
Disclosure of medical errors involving gametes and embryos: an Ethics Committee opinion (2016)
Medical providers have an ethical duty to disclose clinically significant errors involving gametes and embryos as soon as they are discovered. Clinics also should have written policies in place for reducing and disclosing errors. View the Committee Document
Recommended practices for the management of embryology, andrology, and endocrinology laboratories: a committee opinion (2014)
A general overview for good management practices within the endocrinology, andrology, and embryology laboratories in the United States. View the Recommendation
Informed consent and the use of gametes and embryos for research: a committee opinion (2014)
The ethical conduct of human gamete and embryo research depends upon conscientious application of principles of informed consent. View the Committee Opinion
